Modulation of Baroreflex Function by Rosiglitazone in Prediabetic Hyperglycemic Rats

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Modulation of baroreflex function by rosiglitazone in prediabetic hyperglycemic rats.

Baroreflex sensitivity (BRS) is abnormal in the prediabetic state. This study was conducted to determine effects of chronic rosiglitazone (RSG), an insulin sensitizer, on BRS in prediabetic hyperglycemic (PDH) rats induced by nicotinamide and streptozotocin. The fasting and postprandial blood glucose levels were 5.6-6.9 and 7.8-11.0 mmol/l, respectively. Rats were treated with RSG or saline for...

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ژورنال

عنوان ژورنال: Physiological Research

سال: 2012

ISSN: 1802-9973,0862-8408

DOI: 10.33549/physiolres.932304